Association of Vitamin D Levels in Reproductive Immunologic Disorders
DOI:
https://doi.org/10.70552/pjaai.26.1.15721Abstract
Background: Reproductive health has always been an important part of any discussion about women’s health. Recurrent pregnancy loss (RPL) is a devastating reproductive problem. It affects approximately 0.5 to 1% of women attempting pregnancy and 5% of couples trying to conceive. There are several causes of RPL; however, despite work-up, half of the cases remain unexplained.
Methodology: This is a cross-sectional study using convenience sampling wherein women aged 19-45 years and pregnant patients without a history of abortion were recruited.
Results: A total of 75 women were equally distributed among the women with RPL, women with infertility, and normal pregnant women. Normal pregnant women are significantly younger and have significantly longer sun exposure. Vitamin D deficiency is significantly higher among those with RPL and infertility.
Conclusion: In summary, normal pregnant women are younger and have more sun exposure. In the RPL arm, most of them have 3 abortions. The majority of women with RPL and infertility have hypovitaminosis D, but there is no significant difference in the vitamin D levels with regard to the number of abortions. Vitamin D deficiency is significantly higher in the infertile group. Still, no significant difference in vitamin D insufficiency was observed between the RPL group and the infertility group. Normal pregnant women have significantly higher mean vitamin D.
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Copyright (c) 2026 Karol Anne Camonayan-Flor, MD, Cherie Ocampo-Cervantes, MD, Lara Theresa A. Aleta, MD
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