Linking Nutrition, Immunity and Quality of Life Among Tarlac Senior High School Students

Bases for an Adolescent Health Program Framework

Authors

  • Lorena Apple L. Eustaquio, MD Jecsons Medical Center, Mc Arthur Highway, San Nicolas, Tarlac City, Philippines https://orcid.org/0009-0001-3428-7543
  • Liberiza M. Orseno-Ferrer, MD Jecsons Medical Center, Mc Arthur Highway, San Nicolas, Tarlac City, Philippines

DOI:

https://doi.org/10.70552/pjaai.26.1.16555

Keywords:

adolescent health, nutrition, immune function, Health-Related Quality of Life (HRQoL), Conceptual Framework, Immune Status Questionnaire (ISQ), KIDSCREEN-10 Questionnaire

Abstract

Background: Adolescence, as a developmental phase, has a larger significant role in human nutrition, and immune health plays a vital role in defining their physical and psychosocial well-being. However, there is limited empirical data from the Philippines on identifying the collective effects of nutrition and immune health on health-related quality of life (HRQoL) among senior high school students. To address these gaps according to local needs, designing effective adolescent health programs is a good step forward.

Objectives: The study accomplished five objectives: (1) to assess the nutritional status of senior high school students using anthropometric measures interpreted through CDC growth charts in Tarlac City; (2) assess immune status through a validated immune function questionnaire; (3) determine health-related quality of life in physical, mental, and social dimensions using a standardized tool; (4) examine interrelationships among nutritional status, immune health, and HRQoL; and (5) create a 'conceptual framework' for adolescent health programming at Tarlac National High School.

Methodology: The study employed a quantitative, cross-sectional analytic design to examine the relationships of nutritional status, immune function, and health-related quality of life (HRQoL) among 420 senior high school students, aged 16 to 18, enrolled at Tarlac National High School during the academic year 2024–2025. Nutritional status was assessed based on BMI-for-age and height-for-age percentiles using the CDC growth charts. Immune functioning and health-related quality of life (HRQoL) were evaluated using validated self-report instruments, particularly the Immune Status Questionnaire (ISQ) and the KIDSCREEN-10 Questionnaire.

Results: The study showed that most students have optimal nutritional status, as measured by BMI and height-for-age percentiles, which is positively correlated with stronger immune function (r = .041 and r = .019, respectively; p < .05) and higher scores in HRQoL  (r = .032 and r = .028, respectively; p < .05). This group also reported good to excellent general health and low prevalence of chronic diseases. However, a notable percentage of students were stunted (36.7%), underweight (16.7%),  overweight (6.7%), or obese (5.2%). This documented coexistence of undernutrition and overnutrition reflects the dual burden of malnutrition in adolescents, emphasizing the need for tailored public health strategies.

Conclusion: The study revealed significant interrelationships among nutritional status, immune function, and health-related quality of life (HRQoL) of senior high school students at Tarlac National High School. Therefore, this study developed a conceptual framework entitled T.A.R.L.A.C. Health+ Initiative Program, showing that optimal nutrition enhances immune function and quality of life, supporting a holistic, school-based adolescent health program for improved student well-being.

Author Biographies

Lorena Apple L. Eustaquio, MD , Jecsons Medical Center, Mc Arthur Highway, San Nicolas, Tarlac City, Philippines

Corresponding author: Lorena Apple L. Eustaquio, MD
Department of Pediatrics, Jecsons Medical Center, Mc Arthur Highway, San Nicolas, Tarlac City, Philippines 2300
E-mail: lorenaappleeustaquio@gmail.com
ORCiD:https://orcid.org/0009-0001-3428-7543

Liberiza M. Orseno-Ferrer, MD, Jecsons Medical Center, Mc Arthur Highway, San Nicolas, Tarlac City, Philippines

Department of Pediatrics, Jecsons Medical Center, Mc Arthur Highway, San Nicolas, Tarlac City, Philippines

References

1. World Health Organization. Adolescent health. Accessed November 24, 2024. https://www.who.int/health-topics/adolescent-health#tab=tab_1

2. UNICEF. Adolescents. Accessed November 24, 2024. https://data.unicef.org/topic/adolescents/overview/

3. Kliegman RM, St Geme JW III, Blum NJ, et al., eds. Nelson Textbook of Pediatrics. 21st ed. Elsevier; 2020.

4. Moore Heslin A, McNulty B. Adolescent nutrition and health: characteristics, risk factors and opportunities of an overlooked life stage. Proc Nutr Soc. 2023;82(2):142-56. https://pubmed.ncbi.nlm.nih.gov/36924388 DOI: 10.1017/S0029665123002689 DOI: https://doi.org/10.1017/S0029665123002689

5. Javier C, Malabad C, Maniego ML, et al. Determinants of the youth’s nutritional status in selected areas in the Philippines and opportunities for program development and engagement. Philipp J Sci. 2022;151(1):425-35. https://philjournalsci.dost.gov.ph/determinants-of-the-youths-nutritional-status-in-selected-areas-in-the-philippines-and-opportunities-for-program-development-and-engagement/ DOI: https://doi.org/10.56899/151.01.32

6. Jaleel A, Chilumula M, Chukkala Satya S, et al. The assessment of nutritional status of adolescents aged 15-18 years using BMI cutoffs and BMI Z scores: a secondary analysis of National Family Health Survey-5 (2019-21) data. Cureus. 2024;16(5):e59800. https://pubmed.ncbi.nlm.nih.gov/38846183 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155221 https://doi.org/10.7759/cureus.59800 DOI: https://doi.org/10.7759/cureus.59800

7. U.S. Centers for Disease Control and Prevention. BMI. Accessed November 27, 2024. https://www.cdc.gov/bmi/about/index.html

8. U.S. Centers for Disease Control and Prevention. BMI-for-age as a screening measure. Accessed November 27, 2024. https://www.cdc.gov/growth-chart-training/hcp/using-bmi/screening-measure.html

9. U.S. Centers for Disease Control and Prevention. Nutrition and growth. Published May 15, 2024. Accessed November 27, 2024. https://www.cdc.gov/immigrant-refugee-health/hcp/domestic-guidance/nutrition-and-growth.html

10. World Health Organization. Malnutrition. Published March 1, 2024. Accessed November 24, 2024. https://www.who.int/news-room/fact-sheets/detail/malnutrition

11. World Health Organization. Obesity and overweight. Published March 1, 2024. Accessed November 27, 2024. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweightHampl S, Hassink S, Skinner A, et al. Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity. Pediatrics. 2023;151(2):e2022060640. https://doi.org/10.1542/peds.2022-060640. DOI: https://doi.org/10.1542/peds.2022-060640

12. Hampl SE, Hassink SG, Skinner AC, et al. Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity. Pediatrics. 2023;151(2):e2022060640. https://pubmed.ncbi.nlm.nih.gov/36622115 https://doi.org/10.1542/peds.2022-060640. Erratum in Statement of Correction: Obesity Clinical Practice Guideline. Pediatrics. 2024;153(1):e2023064612. https://doi.org/10.1542/peds.2023-064612. https://pubmed.ncbi.nlm.nih.gov/38161151 DOI: https://doi.org/10.1542/peds.2023-064612

13. Fryar CD, Carroll MD, Afful J. Prevalence of overweight, obesity, and severe obesity among children and adolescents aged 2-19 years: United States, 1963-1965 through 2017-2018. U.S. Centers for Disease Control and Prevention. Published September 5, 2018. Accessed November 27, 2024. https://www.cdc.gov/nchs/data/hestat/obesity-child-17-18/obesity-child.htm

14. UNICEF. UNICEF: Many children and adolescents in the Philippines are not growing up healthily. Published October 16, 2019. Accessed November 29, 2024. https://www.unicef.org/philippines/press-releases/unicef-many-children-and-adolescents-philippines-are-not-growing-healthily

15. Department of Science and Technology–Food and Nutrition Research Institute. Overweight and obese Pinoy teens on the rise. Accessed November 29, 2024. https://fnri.dost.gov.ph/index.php/publications/writers-pool-corner/57-food-and-nutrition/851-overweight-and-obese-pinoy-teens-on-the-rise-dost-fnri

16. Whitfield H, Hargreaves D, Nicholls D, Watt HC, Creese H. Risk factors of persistent adolescent thinness: findings from the UK Millennium Cohort Study. BMC Public Health. 2023;23(1):938. https://pubmed.ncbi.nlm.nih.gov/37226159 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207649 https://doi.org/10.1186/s12889-023-15850-1 DOI: https://doi.org/10.1186/s12889-023-15850-1

17. Fryar CD, Carroll MD, Afful J. Prevalence of underweight among children and adolescents aged 2-19 years: United States, 1963-1965 through 2017-2018. U.S. Centers for Disease Control and Prevention. Published December 16, 2020. Accessed November 29, 2024. https://www.cdc.gov/nchs/data/hestat/underweight-child-17-18/underweight-child.htm

18. World Health Organization. Malnutrition. Accessed November 29, 2024. https://www.who.int/health-topics/malnutrition

19. Dasco ML. Nutritional status of Filipino adolescents, >10-19 years old. Department of Science and Technology–Food and Nutrition Research Institute. Accessed November 29, 2024. https://www.fnri.dost.gov.ph/images/sources/eNNS2018/ADOLESCENTS_and_WRA.pdf

20. Situation of Children Philippines. Nutrition of children and adolescents. Accessed November 30, 2024. https://situationofchildren.org/nutrition-of-children-and-adolescents

21. Amoadu M, Abraham SA, Adams AK, Akoto-Buabeng W, Obeng P, Hagan JE Jr. Risk factors of malnutrition among in-school children and adolescents in developing countries: a scoping review. Children (Basel). 2024;11(4):476. https://pubmed.ncbi.nlm.nih.gov/38671693 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11049343 https://doi.org/10.3390/children11040476 DOI: https://doi.org/10.3390/children11040476

22. Caleyachetty R, Thomas GN, Kengne AP, et al. The double burden of malnutrition among adolescents: analysis of data from the Global School-Based Student Health and Health Behavior in School-Aged Children surveys in 57 low- and middle-income countries. Am J Clin Nutr. 2018;108(2):414-24. https://pubmed.ncbi.nlm.nih.gov/29947727 https://doi.org/10.1093/ajcn/nqy105 DOI: https://doi.org/10.1093/ajcn/nqy105

23. Gaupholm J, Dodd W, Papadopoulos A, Little M. Exploring the double burden of malnutrition at the household level in the Philippines: analysis of National Nutrition Survey data. PLoS One. 2023;18(7):e0288402. https://pubmed.ncbi.nlm.nih.gov/37459316 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351706 https://doi.org/10.1371/journal.pone.0288402 DOI: https://doi.org/10.1371/journal.pone.0288402

24. Norris SA, Frongillo EA, Black MM, et al. Nutrition in adolescent growth and development. Lancet. 2022;399(10320):172-84. https://pubmed.ncbi.nlm.nih.gov/34856190 https://doi.org/10.1016/S0140-6736(21)01590-7 DOI: https://doi.org/10.1016/S0140-6736(21)01590-7

25. Fang X, Henao-Mejia J, Henrickson SE. Obesity and immune status in children. Curr Opin Pediatr. 2020;32(6):805-15. https://pubmed.ncbi.nlm.nih.gov/33105275 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489265 https://doi.org/10.1097/MOP.0000000000000953 DOI: https://doi.org/10.1097/MOP.0000000000000953

26. Dobner J, Kaser S. Body mass index and the risk of infection: from underweight to obesity. Clin Microbiol Infect. 2018;24(1):24-8. https://pubmed.ncbi.nlm.nih.gov/28232162 DOI: 10.1016/j.cmi.2017.02.013 DOI: https://doi.org/10.1016/j.cmi.2017.02.013

27. Méndez López LF, González Llerena JL, Vázquez Rodríguez JA, et al. Dietary modulation of the immune system. Nutrients. 2024;16(24):4363. https://pubmed.ncbi.nlm.nih.gov/39770983 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11676904 DOI: 10.3390/nu16244363 DOI: https://doi.org/10.3390/nu16244363

28. Meade T, Dowswell E. Adolescents' health-related quality of life (HRQoL) changes over time: a three-year longitudinal study. Health Qual Life Outcomes. 2016;14:14. https://pubmed.ncbi.nlm.nih.gov/26810328 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727407 https://doi.org/10.1186/s12955-016-0415-9 DOI: https://doi.org/10.1186/s12955-016-0415-9

29. Befus EG, Helseth S, Mølland E, Westergren T, Fegran L, Haraldstad K. Use of KIDSCREEN health-related quality of life instruments in the general population of children and adolescents: a scoping review. Health Qual Life Outcomes. 2023;21(1):6. https://pubmed.ncbi.nlm.nih.gov/36670428 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857919 https://doi.org/10.1186/s12955-023-02088-z DOI: https://doi.org/10.1186/s12955-023-02088-z

Downloads

Published

07/04/2026

How to Cite

Eustaquio, L. A., & Orseno-Ferrer, L. (2026). Linking Nutrition, Immunity and Quality of Life Among Tarlac Senior High School Students: Bases for an Adolescent Health Program Framework. Philippine Journal of Allergy, Asthma and Immunology, 26(1), 1–7. https://doi.org/10.70552/pjaai.26.1.16555