Perfect Combination

Reproductive Immunology Meets Lifestyle Medicine

Authors

  • Odelind S. Conchada-Flores, MD, FPOGS, FPSMFM, FPSUOG Adventist Medical Center Manila, Pasay City, Philippines

DOI:

https://doi.org/10.70552/pjaai.26.1.18330

Keywords:

lifestyle medicine, reproductive immunology, therapeutic lifestyle

Abstract

Reproductive immunologists navigate the complex pathways of endothelial dysfunction, autoantibodies, oxidative stress, and cytokine networks to overcome recurrent pregnancy loss and implantation failure. However, a hopeful dimension is rapidly shifting from the sidelines to the center of reproductive medicine: Lifestyle Medicine.

References

1. American College of Lifestyle Medicine. What is lifestyle medicine? https://lifestylemedicine.org/what-is-lifestyle-medicine/

2. Donato M, Capalbo A, Morizio E, et al. The role of lifestyle intervention in female fertility: a modifiable factor for preconception health. Nutrients. 2025;17(13):2101. https://pubmed.ncbi.nlm.nih.gov/40647206 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12251342 https://doi.org/10.3390/nu17132101

3. Balawender K, Orkisz S. The impact of selected modifiable lifestyle factors on male fertility in the modern world. Cent European J Urol. 2020;73(4):563-8. https://pubmed.ncbi.nlm.nih.gov/33552585 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848840 https://doi.org/10.5173/ceju.2020.1975

4. Braga DPAF, Halpern G, Setti AS, Figueira RCS, Iaconelli A Jr, Borges E Jr. The impact of food intake and social habits on embryo quality and the likelihood of blastocyst formation. Reprod Biomed Online. 2015;31(1):30-8. https://pubmed.ncbi.nlm.nih.gov/25982093 https://doi.org/10.1016/j.rbmo.2015.03.007

5. Hoek J, Schoenmakers S, Baart EB, et al. Preconceptional maternal vegetable intake and paternal smoking are associated with pre-implantation embryo quality. Reprod Sci. 2020;27(11):2018-28. https://pubmed.ncbi.nlm.nih.gov/32542536 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522074 https://doi.org/10.1007/s43032-020-00220-8

6. Hauser ME, McMacken M, Lim A, Shetty P. Nutrition-An evidence-based, practical approach to chronic disease prevention and treatment. J Fam Pract. 2022;71(Suppl 1 Lifestyle):S5-16. https://pubmed.ncbi.nlm.nih.gov/35389838 https://doi.org/10.12788/jfp.0292

7. Cohen S, Miller GE, Rabin BS. Psychological stress and antibody response to immunization: a critical review of the human literature. Psychosom Med. 2001;63(1):7-18. https://pubmed.ncbi.nlm.nih.gov/11211068 https://doi.org/10.1097/00006842-200101000-00002

8. Mínguez-Alarcón L, Chavarro JE, Gaskins AJ. Caffeine, alcohol, smoking, and reproductive outcomes among couples undergoing assisted reproductive technology treatments. Fertil Steril. 2018;110(4):587-92. https://pubmed.ncbi.nlm.nih.gov/30196942 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11002791 https://doi.org/10.1016/j.fertnstert.2018.05.026

9. Okechukwu CE. Does the use of mobile phone affect male fertility? A mini-review. J Hum Reprod Sci. 2020;13(3):174-83. https://pubmed.ncbi.nlm.nih.gov/:33311902 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727890 https://doi.org/10.4103/jhrs.JHRS_126_19

10. Valliant GE. Triumphs of experience: the men of the Harvard Grant Study. Harvard University Press; 2012. https://doi.org/10.4159/harvard.9780674067424

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Published

07/06/2026

How to Cite

Conchada-Flores, O. (2026). Perfect Combination: Reproductive Immunology Meets Lifestyle Medicine. Philippine Journal of Allergy, Asthma and Immunology, 26(1), 1–2. https://doi.org/10.70552/pjaai.26.1.18330